1. Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation. Gong Y, Ma Y, Sinyuk M, Loganathan S, Thompson RC, Sarkaria JN, Chen W, Lathia JD, Mobley BC, Clark SW, Wang J (2016) Neuro Oncol 18(1): 48-57
    › Primary publication · 26136493 (PubMed) · PMC4677408 (PubMed Central)
  2. FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation. Li M, Page-McCaw P, Chen W (2016) Diabetes 65(1): 96-109
    › Primary publication · 26420862 (PubMed) · PMC4686947 (PubMed Central)
  3. Active medulloblastoma enhancers reveal subgroup-specific cellular origins. Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz HJ, Worst BC, Ju B, Orr BA, Zeid R, Polaski DR, Segura-Wang M, Waszak SM, Jones DT, Kool M, Hovestadt V, Buchhalter I, Sieber L, Johann P, Chavez L, Gröschel S, Ryzhova M, Korshunov A, Chen W, Chizhikov VV, Millen KJ, Amstislavskiy V, Lehrach H, Yaspo ML, Eils R, Lichter P, Korbel JO, Pfister SM, Bradner JE, Northcott PA (2016) Nature 530(7588): 57-62
    › Primary publication · 26814967 (PubMed) · PMC5168934 (PubMed Central)
  4. Skeletal muscle insulin resistance in zebrafish induces alterations in β-cell number and glucose tolerance in an age- and diet-dependent manner. Maddison LA, Joest KE, Kammeyer RM, Chen W (2015) Am J Physiol Endocrinol Metab 308(8): E662-9
    › Primary publication · 25670827 (PubMed) · PMC4398831 (PubMed Central)
  5. Oncogenic KRAS promotes malignant brain tumors in zebrafish. Ju B, Chen W, Orr BA, Spitsbergen JM, Jia S, Eden CJ, Henson HE, Taylor MR (2015) Mol Cancer : 18
    › Primary publication · 25644510 (PubMed) · PMC4320811 (PubMed Central)
  6. Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs. Yin L, Maddison LA, Li M, Kara N, LaFave MC, Varshney GK, Burgess SM, Patton JG, Chen W (2015) Genetics 200(2): 431-41
    › Primary publication · 25855067 (PubMed) · PMC4492370 (PubMed Central)
  7. High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9. Varshney GK, Pei W, LaFave MC, Idol J, Xu L, Gallardo V, Carrington B, Bishop K, Jones M, Li M, Harper U, Huang SC, Prakash A, Chen W, Sood R, Ledin J, Burgess SM (2015) Genome Res 25(7): 1030-42
    › Primary publication · 26048245 (PubMed) · PMC4484386 (PubMed Central)
  8. Glucagon receptor inactivation leads to α-cell hyperplasia in zebrafish. Li M, Dean ED, Zhao L, Nicholson WE, Powers AC, Chen W (2015) J Endocrinol 227(2): 93-103
    › Primary publication · 26446275 (PubMed) · PMC4598637 (PubMed Central)
  9. Generation of Targeted Mutations in Zebrafish Using the CRISPR/Cas System. Yin L, Jao LE, Chen W (2015) Methods Mol Biol : 205-17
    › Primary publication · 26285757 (PubMed)
  10. Circadian modulation of dopamine levels and dopaminergic neuron development contributes to attention deficiency and hyperactive behavior. Huang J, Zhong Z, Wang M, Chen X, Tan Y, Zhang S, He W, He X, Huang G, Lu H, Wu P, Che Y, Yan YL, Postlethwait JH, Chen W, Wang H (2015) J Neurosci 35(6): 2572-87
    › Primary publication · 25673850 (PubMed) · PMC4323534 (PubMed Central)