James Crowe
Faculty Member
Last active: 3/31/2019

  1. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model. Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE, de Silva AM, Ting JP (2015) PLoS One 10(8): e0136708
    › Primary publication · 26301593 (PubMed) · PMC4547738 (PubMed Central)
  2. Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth. Willis JR, Sapparapu G, Murrell S, Julien JP, Singh V, King HG, Xia Y, Pickens JA, LaBranche CC, Slaughter JC, Montefiori DC, Wilson IA, Meiler J, Crowe JE (2015) J Clin Invest 125(6): 2523-31
    › Primary publication · 25985274 (PubMed) · PMC4497764 (PubMed Central)
  3. Mechanism of human antibody-mediated neutralization of Marburg virus. Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, Crowe JE (2015) Cell 160(5): 893-903
    › Primary publication · 25723164 (PubMed) · PMC4344968 (PubMed Central)
  4. Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus. Smith SA, Silva LA, Fox JM, Flyak AI, Kose N, Sapparapu G, Khomandiak S, Khomadiak S, Ashbrook AW, Kahle KM, Fong RH, Swayne S, Doranz BJ, McGee CE, Heise MT, Pal P, Brien JD, Austin SK, Diamond MS, Dermody TS, Crowe JE (2015) Cell Host Microbe 18(1): 86-95
    › Primary publication · 26159721 (PubMed) · PMC4501771 (PubMed Central)
  5. Influenza viruses with receptor-binding N1 neuraminidases occur sporadically in several lineages and show no attenuation in cell culture or mice. Hooper KA, Crowe JE, Bloom JD (2015) J Virol 89(7): 3737-45
    › Primary publication · 25609803 (PubMed) · PMC4403400 (PubMed Central)
  6. Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis. Hotard AL, Lee S, Currier MG, Crowe JE, Sakamoto K, Newcomb DC, Peebles RS, Plemper RK, Moore ML (2015) J Virol 89(1): 512-22
    › Primary publication · 25339762 (PubMed) · PMC4301159 (PubMed Central)
  7. Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences. Sevy AM, Jacobs TM, Crowe JE, Meiler J (2015) PLoS Comput Biol 11(7): e1004300
    › Primary publication · 26147100 (PubMed) · PMC4493036 (PubMed Central)
  8. DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JS, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM (2015) Science 349(6243): 88-91
    › Primary publication · 26138979 (PubMed) · PMC4672004 (PubMed Central)
  9. Deciphering the human immunome. Crowe JE, Koff WC (2015) Expert Rev Vaccines 14(11): 1421-5
    › Primary publication · 26485213 (PubMed)
  10. Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity. Long F, Fong RH, Austin SK, Chen Z, Klose T, Fokine A, Liu Y, Porta J, Sapparapu G, Akahata W, Doranz BJ, Crowe JE, Diamond MS, Rossmann MG (2015) Proc Natl Acad Sci U S A 112(45): 13898-903
    › Primary publication · 26504196 (PubMed) · PMC4653152 (PubMed Central)