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James Crowe
Faculty Member
Last active: 3/31/2019

  1. Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth. Chukwuma VU, Kose N, Sather DN, Sapparapu G, Falk R, King H, Singh V, Lampley R, Malherbe DC, Ditto NT, Sullivan JT, Barnes T, Doranz BJ, Labranche CC, Montefiori DC, Kalams SA, Haigwood NL, Crowe JE (2018) PLoS One 13(12): e0209437
    › Primary publication · 30566528 (PubMed) · PMC6300260 (PubMed Central)
  2. HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. Flyak AI, Ruiz S, Colbert MD, Luong T, Crowe JE, Bailey JR, Bjorkman PJ (2018) Cell Host Microbe 24(5): 703-716.e3
    › Primary publication · 30439340 (PubMed) · PMC6258177 (PubMed Central)
  3. Current Understanding of Humoral Immunity to Enterovirus D68. Vogt MR, Crowe JE (2018) J Pediatric Infect Dis Soc 7(suppl_2): S49-S53
    › Primary publication · 30590621 (PubMed)
  4. Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection. Kinchen VJ, Zahid MN, Flyak AI, Soliman MG, Learn GH, Wang S, Davidson E, Doranz BJ, Ray SC, Cox AL, Crowe JE, Bjorkman PJ, Shaw GM, Bailey JR (2018) Cell Host Microbe 24(5): 717-730.e5
    › Primary publication · 30439341 (PubMed) · PMC6250073 (PubMed Central)
  5. Treating Flu with Skin of Frog. Crowe JE (2017) Immunity 46(4): 517-518
    › Primary publication · 28423328 (PubMed)
  6. Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis. Miner JJ, Cook LE, Hong JP, Smith AM, Richner JM, Shimak RM, Young AR, Monte K, Poddar S, Crowe JE, Lenschow DJ, Diamond MS (2017) Sci Transl Med 9(375)
    › Primary publication · 28148840 (PubMed) · PMC5448557 (PubMed Central)
  7. Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody. Mire CE, Geisbert JB, Borisevich V, Fenton KA, Agans KN, Flyak AI, Deer DJ, Steinkellner H, Bohorov O, Bohorova N, Goodman C, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Crowe JE, Zeitlin L, Geisbert TW (2017) Sci Transl Med 9(384)
    › Primary publication · 28381540 (PubMed) · PMC5719873 (PubMed Central)
  8. Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques. Broeckel R, Fox JM, Haese N, Kreklywich CN, Sukulpovi-Petty S, Legasse A, Smith PP, Denton M, Corvey C, Krishnan S, Colgin LMA, Ducore RM, Lewis AD, Axthelm MK, Mandron M, Cortez P, Rothblatt J, Rao E, Focken I, Carter K, Sapparapau G, Crowe JE, Diamond MS, Streblow DN (2017) PLoS Negl Trop Dis 11(6): e0005637
    › Primary publication · 28628616 (PubMed) · PMC5491320 (PubMed Central)
  9. Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus. Wen X, Mousa JJ, Bates JT, Lamb RA, Crowe JE, Jardetzky TS (2017) Nat Microbiol : 16272
    › Primary publication · 28134915 (PubMed) · PMC5308794 (PubMed Central)
  10. Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Sangha AK, Dong J, Williamson L, Hashiguchi T, Saphire EO, Crowe JE, Meiler J (2017) Structure 25(12): 1820-1828.e2
    › Primary publication · 29153506 (PubMed) · PMC5718948 (PubMed Central)