James Crowe
Faculty Member
Last active: 3/14/2018

  1. Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms. Mankowski MC, Kinchen VJ, Wasilewski LN, Flyak AI, Ray SC, Crowe JE, Bailey JR (2018) Proc Natl Acad Sci U S A 115(1): E82-E91
    › Primary publication · 29255018 (PubMed) · PMC5776832 (PubMed Central)
  2. Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8. Matho MH, Schlossman A, Gilchuk IM, Miller G, Mikulski Z, Hupfer M, Wang J, Bitra A, Meng X, Xiang Y, Kaever T, Doukov T, Ley K, Crotty S, Peters B, Hsieh-Wilson LC, Crowe JE, Zajonc DM (2018) J Biol Chem 293(1): 390-401
    › Primary publication · 29123031 (PubMed) · PMC5766908 (PubMed Central)
  3. Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Potential for a Universal Influenza Vaccine. Crowe JE (2018) Cold Spring Harb Perspect Biol 10(7)
    › Primary publication · 28663208 (PubMed) · PMC5829045 (PubMed Central)
  4. Integrating linear optimization with structural modeling to increase HIV neutralization breadth. Sevy AM, Panda S, Crowe JE, Meiler J, Vorobeychik Y (2018) PLoS Comput Biol 14(2): e1005999
    › Primary publication · 29451898 (PubMed) · PMC5833279 (PubMed Central)
  5. Treating Flu with Skin of Frog. Crowe JE (2017) Immunity 46(4): 517-518
    › Primary publication · 28423328 (PubMed)
  6. Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis. Miner JJ, Cook LE, Hong JP, Smith AM, Richner JM, Shimak RM, Young AR, Monte K, Poddar S, Crowe JE, Lenschow DJ, Diamond MS (2017) Sci Transl Med 9(375)
    › Primary publication · 28148840 (PubMed) · PMC5448557 (PubMed Central)
  7. Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody. Mire CE, Geisbert JB, Borisevich V, Fenton KA, Agans KN, Flyak AI, Deer DJ, Steinkellner H, Bohorov O, Bohorova N, Goodman C, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Crowe JE, Zeitlin L, Geisbert TW (2017) Sci Transl Med 9(384)
    › Primary publication · 28381540 (PubMed) · PMC5719873 (PubMed Central)
  8. Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques. Broeckel R, Fox JM, Haese N, Kreklywich CN, Sukulpovi-Petty S, Legasse A, Smith PP, Denton M, Corvey C, Krishnan S, Colgin LMA, Ducore RM, Lewis AD, Axthelm MK, Mandron M, Cortez P, Rothblatt J, Rao E, Focken I, Carter K, Sapparapau G, Crowe JE, Diamond MS, Streblow DN (2017) PLoS Negl Trop Dis 11(6): e0005637
    › Primary publication · 28628616 (PubMed) · PMC5491320 (PubMed Central)
  9. Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus. Wen X, Mousa JJ, Bates JT, Lamb RA, Crowe JE, Jardetzky TS (2017) Nat Microbiol : 16272
    › Primary publication · 28134915 (PubMed) · PMC5308794 (PubMed Central)
  10. Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Sangha AK, Dong J, Williamson L, Hashiguchi T, Saphire EO, Crowe JE, Meiler J (2017) Structure 25(12): 1820-1828.e2
    › Primary publication · 29153506 (PubMed) · PMC5718948 (PubMed Central)