Robert Beauchamp
Principal Investigator
Last active: 10/31/2018

  1. Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition. An H, Stoops SL, Deane NG, Zhu J, Zi J, Weaver C, Waterson AG, Zijlstra A, Lindsley CW, Beauchamp RD (2015) Oncotarget 6(26): 22934-48
    › Citation · 26082441 (PubMed) · PMC4673210 (PubMed Central)
  2. Optimization of a small molecule probe that restores e-cadherin expression. Brogan JT, Stoops SL, Brady S, An H, Weaver C, Daniels JS, Beauchamp RD, Lindsley CW, Waterson AG (2015) Bioorg Med Chem Lett 25(19): 4260-4
    › Primary publication · 26299347 (PubMed) · PMC4567403 (PubMed Central)
  3. Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressiveness. French CL, Ye F, Revetta F, Zhang B, Coffey RJ, Washington MK, Deane NG, Beauchamp RD, Weaver AM (2015) F1000Res : 99
    › Citation · 26097693 (PubMed) · PMC4457132 (PubMed Central)
  4. Claudin-7 expression induces mesenchymal to epithelial transformation (MET) to inhibit colon tumorigenesis. Bhat AA, Pope JL, Smith JJ, Ahmad R, Chen X, Washington MK, Beauchamp RD, Singh AB, Dhawan P (2015) Oncogene 34(35): 4570-80
    › Citation · 25500541 (PubMed) · PMC4804637 (PubMed Central)
  5. Nuclear factor of activated T-cell activity is associated with metastatic capacity in colon cancer. Tripathi MK, Deane NG, Zhu J, An H, Mima S, Wang X, Padmanabhan S, Shi Z, Prodduturi N, Ciombor KK, Chen X, Washington MK, Zhang B, Beauchamp RD (2014) Cancer Res 74(23): 6947-57
    › Primary publication · 25320007 (PubMed) · PMC4252979 (PubMed Central)
  6. Minority Underrepresentation in Academia: Factors Impacting Careers of Surgery Residents. Julien JS, Lang R, Brown TN, Aldrich MC, Deppen SA, Wu H, Feurer ID, Tarpley M, Hill G, Tarpley J, Beauchamp RD, Grogan EL (2014) J Racial Ethn Health Disparities 1(4): 238-246
    › Citation · 25396113 (PubMed) · PMC4226069 (PubMed Central)
  7. Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction. Shi C, Washington MK, Chaturvedi R, Drosos Y, Revetta FL, Weaver CJ, Buzhardt E, Yull FE, Blackwell TS, Sosa-Pineda B, Whitehead RH, Beauchamp RD, Wilson KT, Means AL (2014) Lab Invest 94(4): 409-21
    › Primary publication · 24535260 (PubMed) · PMC3992484 (PubMed Central)
  8. Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling. Pope JL, Bhat AA, Sharma A, Ahmad R, Krishnan M, Washington MK, Beauchamp RD, Singh AB, Dhawan P (2014) Gut 63(4): 622-34
    › Primary publication · 23766441 (PubMed) · PMC4083824 (PubMed Central)
  9. Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma. Al-Greene NT, Means AL, Lu P, Jiang A, Schmidt CR, Chakravarthy AB, Merchant NB, Washington MK, Zhang B, Shyr Y, Deane NG, Beauchamp RD (2013) PLoS One 8(7): e69660
    › Primary publication · 23922772 (PubMed) · PMC3726759 (PubMed Central)
  10. Elevated ALCAM shedding in colorectal cancer correlates with poor patient outcome. Hansen AG, Freeman TJ, Arnold SA, Starchenko A, Jones-Paris CR, Gilger MA, Washington MK, Fan KH, Shyr Y, Beauchamp RD, Zijlstra A (2013) Cancer Res 73(10): 2955-64
    › Primary publication · 23539446 (PubMed) · PMC3660148 (PubMed Central)