Robert Beauchamp
Principal Investigator
Last active: 10/31/2018

  1. Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells. Singh AB, Sharma A, Smith JJ, Krishnan M, Chen X, Eschrich S, Washington MK, Yeatman TJ, Beauchamp RD, Dhawan P (2011) Gastroenterology 141(6): 2140-53
    › Primary publication · 21878201 (PubMed) · PMC3395068 (PubMed Central)
  2. BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma. Williams CS, Zhang B, Smith JJ, Jayagopal A, Barrett CW, Pino C, Russ P, Presley SH, Peng D, Rosenblatt DO, Haselton FR, Yang JL, Washington MK, Chen X, Eschrich S, Yeatman TJ, El-Rifai W, Beauchamp RD, Chang MS (2011) J Clin Invest 121(10): 4056-69
    › Primary publication · 21911938 (PubMed) · PMC3195453 (PubMed Central)
  3. Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas. Nam KT, Lee HJ, Smith JJ, Lapierre LA, Kamath VP, Chen X, Aronow BJ, Yeatman TJ, Bhartur SG, Calhoun BC, Condie B, Manley NR, Beauchamp RD, Coffey RJ, Goldenring JR (2010) J Clin Invest 120(3): 840-9
    › Primary publication · 20197623 (PubMed) · PMC2827957 (PubMed Central)
  4. Increased cell migration and plasticity in Nrf2-deficient cancer cell lines. Rachakonda G, Sekhar KR, Jowhar D, Samson PC, Wikswo JP, Beauchamp RD, Datta PK, Freeman ML (2010) Oncogene 29(25): 3703-14
    › Primary publication · 20440267 (PubMed) · PMC2892014 (PubMed Central)
  5. HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability. Krishnan M, Singh AB, Smith JJ, Sharma A, Chen X, Eschrich S, Yeatman TJ, Beauchamp RD, Dhawan P (2010) Oncogene 29(2): 305-12
    › Primary publication · 19881542 (PubMed) · PMC3388773 (PubMed Central)
  6. Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Smith JJ, Deane NG, Wu F, Merchant NB, Zhang B, Jiang A, Lu P, Johnson JC, Schmidt C, Bailey CE, Eschrich S, Kis C, Levy S, Washington MK, Heslin MJ, Coffey RJ, Yeatman TJ, Shyr Y, Beauchamp RD (2010) Gastroenterology 138(3): 958-68
    › Primary publication · 19914252 (PubMed) · PMC3388775 (PubMed Central)
  7. Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS. Xu BJ, Li J, Beauchamp RD, Shyr Y, Li M, Washington MK, Yeatman TJ, Whitehead RH, Coffey RJ, Caprioli RM (2009) Mol Cell Proteomics 8(5): 936-45
    › Primary publication · 19164278 (PubMed) · PMC2689774 (PubMed Central)
  8. Regulation of metastasis in colorectal adenocarcinoma: a collision between development and tumor biology. Smith JJ, Deane NG, Dhawan P, Beauchamp RD (2008) Surgery 144(3): 353-66
    › Primary publication · 18707034 (PubMed) · PMC2594010 (PubMed Central)
  9. Oncogenic Ras and transforming growth factor-beta synergistically regulate AU-rich element-containing mRNAs during epithelial to mesenchymal transition. Kanies CL, Smith JJ, Kis C, Schmidt C, Levy S, Khabar KS, Morrow J, Deane N, Dixon DA, Beauchamp RD (2008) Mol Cancer Res 6(7): 1124-36
    › Primary publication · 18644977 (PubMed) · PMC2572152 (PubMed Central)
  10. Variability of in situ proteomic profiling and implications for study design in colorectal tumors. Li JQ, Xu BJ, Shakhtour B, Deane N, Merchant N, Heslin MJ, Washington K, Coffey RJ, Beauchamp RD, Shyr Y, Billheimer D (2007) Int J Oncol 31(1): 103-11
    › Primary publication · 17549410 (PubMed)