Mark de Caestecker
Associate Professor of Medicine
Last active: 10/23/2018

  1. The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis. Lee DK, Park SH, Yi Y, Choi SG, Lee C, Parks WT, Cho H, de Caestecker MP, Shaul Y, Roberts AB, Kim SJ (2001) Genes Dev 15(4): 455-66
    › Citation · 11230153 (PubMed) · PMC312630 (PubMed Central)
  2. Structural basis of Smad1 activation by receptor kinase phosphorylation. Qin BY, Chacko BM, Lam SS, de Caestecker MP, Correia JJ, Lin K (2001) Mol Cell 8(6): 1303-12
    › Citation · 11779505 (PubMed)
  3. Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases. Parks WT, Frank DB, Huff C, Renfrew Haft C, Martin J, Meng X, de Caestecker MP, McNally JG, Reddi A, Taylor SI, Roberts AB, Wang T, Lechleider RJ (2001) J Biol Chem 276(22): 19332-9
    › Citation · 11279102 (PubMed)
  4. Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension. De Caestecker M, Meyrick B (2001) Respir Res 2(4): 193-7
    › Citation · 11686884 (PubMed) · PMC59576 (PubMed Central)
  5. Zebrafish nma is involved in TGFbeta family signaling. Tsang M, Kim R, de Caestecker MP, Kudoh T, Roberts AB, Dawid IB (2000) Genesis 28(2): 47-57
    › Citation · 11064421 (PubMed)
  6. The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain. de Caestecker MP, Yahata T, Wang D, Parks WT, Huang S, Hill CS, Shioda T, Roberts AB, Lechleider RJ (2000) J Biol Chem 275(3): 2115-22
    › Citation · 10636916 (PubMed)
  7. The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors. Yahata T, de Caestecker MP, Lechleider RJ, Andriole S, Roberts AB, Isselbacher KJ, Shioda T (2000) J Biol Chem 275(12): 8825-34
    › Citation · 10722728 (PubMed)
  8. Role of transforming growth factor-beta signaling in cancer. de Caestecker MP, Piek E, Roberts AB (2000) J Natl Cancer Inst 92(17): 1388-402
    › Citation · 10974075 (PubMed)
  9. A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction. Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, Parks WT, Meng X, Lechleider RJ, Wang T, Roberts AB (2000) Genes Dev 14(13): 1605-16
    › Citation · 10887155 (PubMed) · PMC316742 (PubMed Central)
  10. A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif. Larisch S, Yi Y, Lotan R, Kerner H, Eimerl S, Tony Parks W, Gottfried Y, Birkey Reffey S, de Caestecker MP, Danielpour D, Book-Melamed N, Timberg R, Duckett CS, Lechleider RJ, Steller H, Orly J, Kim SJ, Roberts AB (2000) Nat Cell Biol 2(12): 915-21
    › Citation · 11146656 (PubMed)