, a bio/informatics shared resource is still "open for business" - Visit the CDS website


  1. Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2. Tang L, Guo B, Javed A, Choi JY, Hiebert S, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Zhou GW (1999) J Biol Chem 274(47): 33580-6
    › Primary publication · 10559245 (PubMed)
  2. Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein. Fenrick R, Amann JM, Lutterbach B, Wang L, Westendorf JJ, Downing JR, Hiebert SW (1999) Mol Cell Biol 19(10): 6566-74
    › Primary publication · 10490596 (PubMed) · PMC84626 (PubMed Central)
  3. The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation. Westendorf JJ, Yamamoto CM, Lenny N, Downing JR, Selsted ME, Hiebert SW (1998) Mol Cell Biol 18(1): 322-33
    › Primary publication · 9418879 (PubMed) · PMC121499 (PubMed Central)
  4. The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein. Lutterbach B, Sun D, Schuetz J, Hiebert SW (1998) Mol Cell Biol 18(6): 3604-11
    › Primary publication · 9584201 (PubMed) · PMC108942 (PubMed Central)
  5. Role of histone deacetylases in acute leukemia. Fenrick R, Hiebert SW (1998) J Cell Biochem Suppl : 194-202
    › Primary publication · 9893271 (PubMed)
  6. Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1. Petrovick MS, Hiebert SW, Friedman AD, Hetherington CJ, Tenen DG, Zhang DE (1998) Mol Cell Biol 18(7): 3915-25
    › Primary publication · 9632776 (PubMed) · PMC108976 (PubMed Central)
  7. Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains. Zeng C, McNeil S, Pockwinse S, Nickerson J, Shopland L, Lawrence JB, Penman S, Hiebert S, Lian JB, van Wijnen AJ, Stein JL, Stein GS (1998) Proc Natl Acad Sci U S A 95(4): 1585-9
    › Primary publication · 9465059 (PubMed) · PMC19104 (PubMed Central)
  8. ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Lutterbach B, Westendorf JJ, Linggi B, Patten A, Moniwa M, Davie JR, Huynh KD, Bardwell VJ, Lavinsky RM, Rosenfeld MG, Glass C, Seto E, Hiebert SW (1998) Mol Cell Biol 18(12): 7176-84
    › Primary publication · 9819404 (PubMed) · PMC109299 (PubMed Central)
  9. E2F-1 and E2F-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation. Strom DK, Cleveland JL, Chellappan S, Nip J, Hiebert SW (1998) Cell Growth Differ 9(1): 59-69
    › Primary publication · 9438389 (PubMed)
  10. CBFa(AML/PEBP2)-related elements in the TGF-beta type I receptor promoter and expression with osteoblast differentiation. Ji C, Casinghino S, Chang DJ, Chen Y, Javed A, Ito Y, Hiebert SW, Lian JB, Stein GS, McCarthy TL, Centrella M (1998) J Cell Biochem 69(3): 353-63
    › Primary publication · 9581873 (PubMed)