NOTICE: Labnodes will be unavailable on Sunday March 4th for scheduled maintenance from 6-11AM central time.
  1. c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis. Sánchez-Arévalo Lobo VJ, Fernández LC, Carrillo-de-Santa-Pau E, Richart L, Cobo I, Cendrowski J, Moreno U, Del Pozo N, Megías D, Bréant B, Wright CV, Magnuson M, Real FX (2017) Gut
    › Primary publication · 28159836 (PubMed)
  2. Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A. Hoang CQ, Hale MA, Azevedo-Pouly AC, Elsässer HP, Deering TG, Willet SG, Pan FC, Magnuson MA, Wright CV, Swift GH, MacDonald RJ (2016) Mol Cell Biol 36(24): 3033-3047
    › Primary publication · 27697859 (PubMed) · PMC5126291 (PubMed Central)
  3. Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function. Henley KD, Stanescu DE, Kropp PA, Wright CV, Won KJ, Stoffers DA, Gannon M (2016) Cell Rep 15(12): 2637-50
    › Primary publication · 27292642 (PubMed) · PMC4917419 (PubMed Central)
  4. The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine-cell specification and postnatal β-cell maturation. Yang YP, Magnuson MA, Stein R, Wright CV (2016) Development
    › Primary publication · 27993987 (PubMed)
  5. Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells. Bechard ME, Bankaitis ED, Hipkens SB, Ustione A, Piston DW, Yang YP, Magnuson MA, Wright CV (2016) Genes Dev 30(16): 1852-65
    › Primary publication · 27585590 (PubMed) · PMC5024683 (PubMed Central)
  6. PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance. Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, Dawson DW, Biankin AV, Hebrok M, Crawford HC (2016) Genes Dev 30(24): 2669-2683
    › Primary publication · 28087712 (PubMed) · PMC5238727 (PubMed Central)
  7. New ideas connecting the cell cycle and pancreatic endocrine-lineage specification. Bechard ME, Wright CV (2016) Cell Cycle
    › Primary publication · 27860540 (PubMed)
  8. Foxl1-expressing mesenchymal cells constitute the intestinal stem cell niche. Aoki R, Shoshkes-Carmel M, Gao N, Shin S, May CL, Golson ML, Zahm AM, Ray M, Wiser CL, Wright CV, Kaestner KH (2016) Cell Mol Gastroenterol Hepatol 2(2): 175-188
    › Primary publication · 26949732 (PubMed) · PMC4772878 (PubMed Central)
  9. Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice. Kodama S, Nakano Y, Hirata K, Furuyama K, Horiguchi M, Kuhara T, Masui T, Kawaguchi M, Gannon M, Wright CV, Uemoto S, Kawaguchi Y (2016) Sci Rep : 21211
    › Primary publication · 26887806 (PubMed) · PMC4758062 (PubMed Central)
  10. The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma. Krah NM, De La O JP, Swift GH, Hoang CQ, Willet SG, Chen Pan F, Cash GM, Bronner MP, Wright CV, MacDonald RJ, Murtaugh LC (2015) Elife
    › Primary publication · 26151762 (PubMed) · PMC4536747 (PubMed Central)