Aaron Bowman
Associate Professor, Pediatrics, Neurology and Biochemistry
Last active: 4/11/2018

  1. Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line. Bryan MR, Uhouse MA, Nordham KD, Joshi P, Rose DIR, O'Brien MT, Aschner M, Bowman AB (2018) Neurotoxicology : 185-194
    › Primary publication · 28780388 (PubMed) · PMC5796869 (PubMed Central)
  2. Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells. Dos Santos AA, López-Granero C, Farina M, Rocha JBT, Bowman AB, Aschner M (2018) Food Chem Toxicol : 328-336
    › Primary publication · 29428217 (PubMed)
  3. Relationships Between Essential Manganese Biology and Manganese Toxicity in Neurological Disease. Pfalzer AC, Bowman AB (2017) Curr Environ Health Rep 4(2): 223-228
    › Primary publication · 28417441 (PubMed) · PMC5515274 (PubMed Central)
  4. Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model. Bichell TJV, Wegrzynowicz M, Tipps KG, Bradley EM, Uhouse MA, Bryan M, Horning K, Fisher N, Dudek K, Halbesma T, Umashanker P, Stubbs AD, Holt HK, Kwakye GF, Tidball AM, Colbran RJ, Aschner M, Neely MD, Di Pardo A, Maglione V, Osmand A, Bowman AB (2017) Biochim Biophys Acta Mol Basis Dis 1863(6): 1596-1604
    › Primary publication · 28213125 (PubMed) · PMC5515276 (PubMed Central)
  5. Phenotypic Discordance in Siblings with Identical Compound Heterozygous PARK2 Mutations. Isaacs D, Claassen D, Bowman AB, Hedera P (2017) Brain Sci 7(7)
    › Primary publication · 28672806 (PubMed) · PMC5532584 (PubMed Central)
  6. Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders. Bryan MR, Bowman AB (2017) Adv Neurobiol : 113-142
    › Primary publication · 28889265 (PubMed) · PMC6559248 (PubMed Central)
  7. Heterozygous loss of TSC2 alters p53 signaling and human stem cell reprogramming. Armstrong LC, Westlake G, Snow JP, Cawthon B, Armour E, Bowman AB, Ess KC (2017) Hum Mol Genet 26(23): 4629-4641
    › Primary publication · 28973543 (PubMed) · PMC5886307 (PubMed Central)
  8. From the Cover: Manganese and Rotenone-Induced Oxidative Stress Signatures Differ in iPSC-Derived Human Dopamine Neurons. Neely MD, Davison CA, Aschner M, Bowman AB (2017) Toxicol Sci 159(2): 366-379
    › Primary publication · 28962525 (PubMed) · PMC5837701 (PubMed Central)
  9. Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease. Di Pardo A, Amico E, Basit A, Armirotti A, Joshi P, Neely MD, Vuono R, Castaldo S, Digilio AF, Scalabrì F, Pepe G, Elifani F, Madonna M, Jeong SK, Park BM, D'Esposito M, Bowman AB, Barker RA, Maglione V (2017) Sci Rep 7(1): 5280
    › Primary publication · 28706199 (PubMed) · PMC5509685 (PubMed Central)
  10. BXD recombinant inbred strains participate in social preference, anxiety and depression behaviors along sex-differences in cytokines and tactile allodynia. López-Granero C, Antunes Dos Santos A, Ferrer B, Culbreth M, Chakraborty S, Barrasa A, Gulinello M, Bowman AB, Aschner M (2017) Psychoneuroendocrinology : 92-98
    › Primary publication · 28324704 (PubMed) · PMC5985819 (PubMed Central)