Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.

Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, Stein RW, Brissova M, Powers AC
J Clin Invest. 2019 129 (1): 246-251

PMID: 30507613 · PMCID: PMC6307934 · DOI:10.1172/JCI121994

MeSH Terms (10)

Adolescent Adult Diabetes Mellitus, Type 1 Genetic Variation Hepatocyte Nuclear Factor 1-alpha Heterozygote Humans Insulin-Secreting Cells Male Transcription, Genetic

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