Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose.

Shiota C, Larsson O, Shelton KD, Shiota M, Efanov AM, Hoy M, Lindner J, Kooptiwut S, Juntti-Berggren L, Gromada J, Berggren PO, Magnuson MA
J Biol Chem. 2002 277 (40): 37176-83

PMID: 12149271 · DOI:10.1074/jbc.M206757200

MeSH Terms (21)

Animals ATP-Binding Cassette Transporters Blood Glucose Carbachol Cloning, Molecular Eating Exocytosis Genotype Glucose Clamp Technique Insulin Insulin Secretion Islets of Langerhans Mice Mice, Knockout Molecular Sequence Data Perfusion Potassium Channels Potassium Channels, Inwardly Rectifying Receptors, Drug Recombinant Proteins Sulfonylurea Receptors

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