Lars Plate
Last active: 3/3/2020

Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.

Schonhoft JD, Monteiro C, Plate L, Eisele YS, Kelly JM, Boland D, Parker CG, Cravatt BF, Teruya S, Helmke S, Maurer M, Berk J, Sekijima Y, Novais M, Coelho T, Powers ET, Kelly JW
Sci Transl Med. 2017 9 (407)

PMID: 28904227 · PMCID: PMC5628019 · DOI:10.1126/scitranslmed.aam7621

MeSH Terms (19)

Amyloidosis, Familial Benzoxazoles Case-Control Studies Cross-Linking Reagents Diazomethane Genotype Humans Ions Light Molecular Probes Molecular Weight Peptides Prealbumin Protein Folding Protein Multimerization Protein Structure, Secondary Proteolysis Proteomics Solubility

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