Jeff Reese
Last active: 1/7/2021

Diagnosis and Management of Patent Ductus Arteriosus.

Gillam-Krakauer M, Reese J
Neoreviews. 2018 19 (7): e394-e402

PMID: 30505242 · PMCID: PMC6269146 · DOI:10.1542/neo.19-7-e394

Preterm infants are at increased risk for patent ductus arteriosus (PDA). Prolonged exposure to PDA may be deleterious and has been associated with neonatal morbidity and mortality. Although the molecular mechanisms underlying regulation of postnatal ductus arteriosus closure are not fully understood, clinical experience and research trials have informed recent changes in PDA management strategies and refocused treatment strategies on smaller subsets of infants who require intervention. This review examines current diagnostic and management approaches to PDA in preterm neonates.

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