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Jeff Reese
Last active: 1/7/2021

Raman spectroscopy provides a noninvasive approach for determining biochemical composition of the pregnant cervix in vivo.

O'Brien CM, Vargis E, Paria BC, Bennett KA, Mahadevan-Jansen A, Reese J
Acta Paediatr. 2014 103 (7): 715-21

PMID: 24628401 · PMCID: PMC4048629 · DOI:10.1111/apa.12630

UNLABELLED - The molecular changes that occur with cervical remodelling during pregnancy are not completely understood. This study reviews Raman spectroscopy, an optical technique for detecting changes in the pregnant cervix, and reports preliminary studies on cervical remodelling in mice that suggest that the technique provides advantages over other methods.

CONCLUSION - Raman spectroscopy is sensitive to biochemical changes in the pregnant cervix and has high potential as a tool for detecting premature cervical remodelling in pregnant women.

©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

MeSH Terms (8)

Animals Cervical Ripening Cervix Uteri Female Humans Pregnancy Spectrum Analysis, Raman Uterine Cervical Diseases

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