Glutamate-oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux.

Egnatchik RA, Leamy AK, Sacco SA, Cheah YE, Shiota M, Young JD
J Biol Chem. 2019 294 (9): 3081-3090

PMID: 30563841 · PMCID: PMC6398133 · DOI:10.1074/jbc.RA118.004869

MeSH Terms (15)

Animals Aspartate Aminotransferases Cell Death Cell Line Citric Acid Cycle Extracellular Space Glutamine Hepatocytes Ketoglutaric Acids Male Oxidative Stress Oxygen Palmitates Rats Rats, Sprague-Dawley

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