Kevin Schey
Last active: 3/24/2020

Publication

Back cover: Imaging mass spectrometry of the visual system: Advancing the molecular understanding of retina degenerations.

Bowrey HE, Anderson DM, Pallitto P, Gutierrez DB, Fan J, Crouch RK, Schey KL, Ablonczy Z
Proteomics Clin Appl. 2016 10 (4): NA

PMID: 27061327 · DOI:10.1002/prca.201670043

DOI: 10.1002/prca.201500103 Damage associated with the bisretinoid, A2E, has been implicated in blinding diseases. Imaging mass spectrometry of flat mounted retinal pigment epithelial tissue from mice, rabbits, macaques, and humans provided evidence that the distribution of A2E depends on retina and eye anatomy. These comparative data support the idea that elevated levels of A2E are indicative of reduced metabolic activity in the retina. Further details can be found in the article by Hannah E. Bowrey et al. on page 391.

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