Kevin Osteen
Last active: 2/19/2015

The immunoconjugate "icon" targets aberrantly expressed endothelial tissue factor causing regression of endometriosis.

Krikun G, Hu Z, Osteen K, Bruner-Tran KL, Schatz F, Taylor HS, Toti P, Arcuri F, Konigsberg W, Garen A, Booth CJ, Lockwood CJ
Am J Pathol. 2010 176 (2): 1050-6

PMID: 20042667 · PMCID: PMC2808107 · DOI:10.2353/ajpath.2010.090757

MeSH Terms (20)

Adult Animals CHO Cells Cricetinae Cricetulus Drug Delivery Systems Endometriosis Endothelium, Vascular Female Humans Immunoconjugates Immunoglobulin Fc Fragments Immunotherapy Mice Mice, Nude Middle Aged Neovascularization, Pathologic Peritoneal Diseases Thromboplastin Transplantation, Heterologous

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