John Wikswo
Faculty Member
Last active: 2/19/2015

Universal serial bus powered and controlled isolated constant-current physiological stimulator.

Holcomb MR, Bekele RY, Lima EA, Wikswo JP
Rev Sci Instrum. 2008 79 (12): 126103

PMID: 19123594 · PMCID: PMC2736648 · DOI:10.1063/1.3030861

We have developed a compact, isolated, physiological, constant-current stimulator that is powered and controlled by a universal serial bus (USB) interface. The stimulator is designed to be used in ex vivo cardiac experiments but is suitable for a wide variety of settings. The cost and features compare very favorably with commercial stimulators usually used in research and student laboratories. In addition to being USB powered, other novel aspects of our stimulator include the ability to produce large currents, up to 100 mA through a typical 1 kOmega load, by means of a single high-voltage dc-to-dc converter; user-specified variable period, magnitude, and duration of complex monophasic or biphasic sequences; and easy integration via hardware or software into existing experimental setups.

MeSH Terms (10)

Computers Computer Simulation Electricity Electric Power Supplies Electric Stimulation Electrophysiology Equipment Design Materials Testing Signal Processing, Computer-Assisted Software

Connections (3)

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