Michael Waterman
Faculty Member
Last active: 2/12/2015

Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Delta7-24, 25-dihydrolanosterol.

Hargrove TY, Wawrzak Z, Liu J, Waterman MR, Nes WD, Lepesheva GI
J Lipid Res. 2012 53 (2): 311-20

PMID: 22135275 · PMCID: PMC3269163 · DOI:10.1194/jlr.M021865

MeSH Terms (12)

14-alpha Demethylase Inhibitors Binding Sites Crystallography, X-Ray Dose-Response Relationship, Drug Enzyme Activation Lanosterol Models, Molecular Mutation Protein Conformation Sterol 14-Demethylase Trypanocidal Agents Trypanosoma brucei brucei

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