Michael Waterman
Faculty Member
Last active: 2/12/2015

Structural diversities of active site in clinical azole-bound forms between sterol 14alpha-demethylases (CYP51s) from human and Mycobacterium tuberculosis.

Matsuura K, Yoshioka S, Tosha T, Hori H, Ishimori K, Kitagawa T, Morishima I, Kagawa N, Waterman MR
J Biol Chem. 2005 280 (10): 9088-96

PMID: 15611056 · DOI:10.1074/jbc.M413042200

MeSH Terms (20)

Amino Acid Sequence Azoles Bacterial Proteins Binding Sites Cytochrome P-450 Enzyme System Heme Humans Kinetics Models, Molecular Molecular Sequence Data Mycobacterium tuberculosis Oxidoreductases Protein Conformation Protein Structure, Secondary Recombinant Proteins Sequence Alignment Sequence Homology, Amino Acid Spectrophotometry Spectrum Analysis, Raman Sterol 14-Demethylase

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