Michael Waterman
Faculty Member
Last active: 2/12/2015

Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.

Holla VR, Adas F, Imig JD, Zhao X, Price E, Olsen N, Kovacs WJ, Magnuson MA, Keeney DS, Breyer MD, Falck JR, Waterman MR, Capdevila JH
Proc Natl Acad Sci U S A. 2001 98 (9): 5211-6

PMID: 11320253 · PMCID: PMC33189 · DOI:10.1073/pnas.081627898

MeSH Terms (24)

Androgens Animals Arachidonic Acid Blood Pressure Castration Cytochrome P-450 CYP4A Cytochrome P-450 Enzyme System Dihydrotestosterone Enzyme Induction Female Gene Deletion Hydroxyeicosatetraenoic Acids Hypertension Kidney Male Mice Mice, Knockout Microsomes Mixed Function Oxygenases Renal Circulation RNA, Messenger Sex Characteristics Testosterone Vascular Resistance

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