Michael Waterman
Faculty Member
Last active: 2/12/2015

Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents.

Lamb DC, Kelly DE, Waterman MR, Stromstedt M, Rozman D, Kelly SL
Yeast. 1999 15 (9): 755-63

PMID: 10398344 · DOI:10.1002/(SICI)1097-0061(19990630)15:9<755::AID-YEA417>3.0.CO;2-8

MeSH Terms (18)

Antifungal Agents Binding Sites Candida albicans Carbon Monoxide Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Enzyme System Formates Humans Inhibitory Concentration 50 Itraconazole Ketoconazole Kinetics Ligands Oxidoreductases Recombinant Proteins Spectrum Analysis Sterol 14-Demethylase Titrimetry

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