Michael Waterman
Faculty Member
Last active: 2/12/2015

Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography.

Podust LM, von Kries JP, Eddine AN, Kim Y, Yermalitskaya LV, Kuehne R, Ouellet H, Warrier T, Alteköster M, Lee JS, Rademann J, Oschkinat H, Kaufmann SH, Waterman MR
Antimicrob Agents Chemother. 2007 51 (11): 3915-23

PMID: 17846131 · PMCID: PMC2151439 · DOI:10.1128/AAC.00311-07

MeSH Terms (14)

Amino Acid Sequence Bacterial Proteins Benzeneacetamides Binding Sites Crystallography, X-Ray Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Enzyme System Enzyme Inhibitors Imidazoles Models, Molecular Molecular Structure Mycobacterium tuberculosis Sequence Homology, Amino Acid Substrate Specificity

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