Michael Waterman
Faculty Member
Last active: 2/12/2015

Three-dimensional structure of steroid 21-hydroxylase (cytochrome P450 21A2) with two substrates reveals locations of disease-associated variants.

Zhao B, Lei L, Kagawa N, Sundaramoorthy M, Banerjee S, Nagy LD, Guengerich FP, Waterman MR
J Biol Chem. 2012 287 (13): 10613-10622

PMID: 22262854 · PMCID: PMC3323056 · DOI:10.1074/jbc.M111.323501

MeSH Terms (10)

17-alpha-Hydroxyprogesterone Adrenal Hyperplasia, Congenital Animals Binding Sites Cattle Crystallography, X-Ray Humans Mutation Steroid 21-Hydroxylase Structure-Activity Relationship

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