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This article explored advantages of canonical correlation using the Multidimensional Health Locus of Control (MHLC) scales in relation to measures of coping, affect and values. Survey data collected from 659 participants demonstrated significant canonical correlations between the MHLC and synthetic variables representing all three of these constructs. Results verified some previously hypothesized relations (e.g. external health control relates to passive coping) and introduced new findings pertaining to the relations between networks of MHLC variables and networks of the other three constructs (e.g. positive affect relates to collaborative control between self and God regarding health). Canonical correlation promotes greater understanding of relations between health loci of control and other multidimensional variables than can be obtained through simpler analytic strategies.