Gong Yang
Faculty Member
Last active: 4/27/2017

Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study.

Villegas R, Gao YT, Yang G, Li HL, Elasy TA, Zheng W, Shu XO
Am J Clin Nutr. 2008 87 (1): 162-7

PMID: 18175751 · PMCID: PMC2361384 · DOI:10.1093/ajcn/87.1.162

BACKGROUND - It has been postulated that a diet high in legumes may be beneficial for the prevention of type 2 diabetes mellitus (type 2 DM). However, data linking type 2 DM risk and legume intake are limited.

OBJECTIVE - The objective of the study was to examine the association between legume and soy food consumption and self-reported type 2 DM.

DESIGN - The study was conducted in a population-based prospective cohort of middle-aged Chinese women. We followed 64,227 women with no history of type 2 DM, cancer, or cardiovascular disease at study recruitment for an average of 4.6 y. Participants completed in-person interviews that collected information on diabetes risk factors, including dietary intake and physical activity in adulthood. Anthropometric measurements were taken. Dietary intake was assessed with a validated food-frequency questionnaire at the baseline survey and at the first follow-up survey administered 2-3 y after study recruitment.

RESULTS - We observed an inverse association between quintiles of total legume intake and 3 mutually exclusive legume groups (peanuts, soybeans, and other legumes) and type 2 DM incidence. The multivariate-adjusted relative risk of type 2 DM for the upper quintile compared with the lower quintile was 0.62 (95% CI: 0.51, 0.74) for total legumes and 0.53 (95% CI: 0.45, 0.62) for soybeans. The association between soy products (other than soy milk) and soy protein consumption (protein derived from soy beans and their products) with type 2 DM was not significant.

CONCLUSIONS - Consumption of legumes, soybeans in particular, was inversely associated with the risk type 2 DM.

MeSH Terms (20)

Adult China Cohort Studies Confidence Intervals Diabetes Mellitus, Type 2 Fabaceae Female Follow-Up Studies Health Surveys Humans Incidence Middle Aged Multivariate Analysis Nutrition Assessment Odds Ratio Prospective Studies Risk Factors Soy Foods Surveys and Questionnaires Women's Health

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