Keith Wilson
Faculty Member
Last active: 7/1/2021

Cyclosporine A enhances leukocyte binding by human intestinal microvascular endothelial cells through inhibition of p38 MAPK and iNOS. Paradoxical proinflammatory effect on the microvascular endothelium.

Rafiee P, Johnson CP, Li MS, Ogawa H, Heidemann J, Fisher PJ, Lamirand TH, Otterson MF, Wilson KT, Binion DG
J Biol Chem. 2002 277 (38): 35605-15

PMID: 12110686 · DOI:10.1074/jbc.M205826200

MeSH Terms (19)

Base Sequence Cell Adhesion Cells, Cultured Cyclosporine DNA Primers Endothelium, Vascular Humans Immunosuppressive Agents Intestines Leukocytes Lipopolysaccharides Mitogen-Activated Protein Kinases NF-kappa B Nitric Oxide Nitric Oxide Synthase Nitric Oxide Synthase Type II p38 Mitogen-Activated Protein Kinases Signal Transduction Tumor Necrosis Factor-alpha

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