Alex Waterson
Faculty Member
Last active: 3/21/2014

Development of potent B-RafV600E inhibitors containing an arylsulfonamide headgroup.

Stellwagen JC, Adjabeng GM, Arnone MR, Dickerson SH, Han C, Hornberger KR, King AJ, Mook RA, Petrov KG, Rheault TR, Rominger CM, Rossanese OW, Smitheman KN, Waterson AG, Uehling DE
Bioorg Med Chem Lett. 2011 21 (15): 4436-40

PMID: 21733693 · DOI:10.1016/j.bmcl.2011.06.021

MeSH Terms (12)

Administration, Oral Amino Acid Substitution Animals Binding Sites Catalytic Domain Fluorine Microsomes, Liver Protein Kinase Inhibitors Proto-Oncogene Proteins B-raf Rats Structure-Activity Relationship Sulfonamides

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