David Tabb
Faculty Member
Last active: 6/26/2014

What's driving false discovery rates?

Tabb DL
J Proteome Res. 2008 7 (1): 45-6

PMID: 18081243 · PMCID: PMC2810656 · DOI:10.1021/pr700728t

The "Paris Guidelines" have begun the process of standardizing reporting for proteomics. New bioinformatics tools have improved the process for estimating error rates of peptide identifications. This perspective seeks to consider these advances in the context of proteomics' short history. As increasing numbers of proteomics papers come from biologists rather than technologists, developing consensus standards for estimating error will be increasingly necessary. Standardizing this assessment should be welcomed as a reflection of the growing impact of proteomic technologies.

MeSH Terms (5)

Algorithms Databases, Protein Models, Statistical Peptides Tandem Mass Spectrometry

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