Rebecca Cook
Faculty Member
Last active: 4/15/2019

Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.

Morrison Joly M, Williams MM, Hicks DJ, Jones B, Sanchez V, Young CD, Sarbassov DD, Muller WJ, Brantley-Sieders D, Cook RS
Breast Cancer Res. 2017 19 (1): 74

PMID: 28666462 · PMCID: PMC5493112 · DOI:10.1186/s13058-017-0868-8

MeSH Terms (21)

Animals Breast Neoplasms Cell Line, Tumor Cell Movement Disease Models, Animal Female Gene Amplification Heterografts Humans Mechanistic Target of Rapamycin Complex 2 Mice Mice, Transgenic Neoplasm Metastasis Neoplasm Staging Prognosis Proto-Oncogene Proteins c-akt rac1 GTP-Binding Protein Rapamycin-Insensitive Companion of mTOR Protein Receptor, ErbB-2 rho Guanine Nucleotide Dissociation Inhibitor beta Signal Transduction

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