Rebecca Cook
Faculty Member
Last active: 4/15/2019

Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence.

Balko JM, Schwarz LJ, Luo N, Estrada MV, Giltnane JM, Dávila-González D, Wang K, Sánchez V, Dean PT, Combs SE, Hicks D, Pinto JA, Landis MD, Doimi FD, Yelensky R, Miller VA, Stephens PJ, Rimm DL, Gómez H, Chang JC, Sanders ME, Cook RS, Arteaga CL
Sci Transl Med. 2016 8 (334): 334ra53

PMID: 27075627 · PMCID: PMC5256931 · DOI:10.1126/scitranslmed.aad3001

MeSH Terms (17)

Antineoplastic Agents Cell Line, Tumor Cell Proliferation Chromosomes, Human, Pair 9 Cohort Studies Female Gene Amplification Gene Knockdown Techniques Genetic Loci Humans Janus Kinase 2 Middle Aged Signal Transduction Spheroids, Cellular STAT3 Transcription Factor STAT6 Transcription Factor Triple Negative Breast Neoplasms

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