Rebecca Cook
Faculty Member
Last active: 4/15/2019

ErbB3 downregulation enhances luminal breast tumor response to antiestrogens.

Morrison MM, Hutchinson K, Williams MM, Stanford JC, Balko JM, Young C, Kuba MG, Sánchez V, Williams AJ, Hicks DJ, Arteaga CL, Prat A, Perou CM, Earp HS, Massarweh S, Cook RS
J Clin Invest. 2013 123 (10): 4329-43

PMID: 23999432 · PMCID: PMC3784526 · DOI:10.1172/JCI66764

MeSH Terms (29)

Animals Antibodies, Monoclonal Antineoplastic Agents, Hormonal Breast Neoplasms Cell Proliferation Cell Survival Down-Regulation Drug Resistance, Neoplasm Drug Synergism ErbB Receptors Estradiol Estrogen Receptor Modulators Female Fulvestrant Gene Dosage Gene Expression Gene Expression Regulation, Neoplastic Humans MCF-7 Cells Mice Mice, Inbred BALB C Mice, Nude Oligonucleotide Array Sequence Analysis Receptor, ErbB-2 Receptor, ErbB-3 Signal Transduction Survival Analysis Transcriptome Xenograft Model Antitumor Assays

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