Dana Cardin
Faculty Member
Last active: 3/18/2014

Treatment of early-stage pancreatic cancer.

Castellanos EH, Cardin DB, Berlin JD
Oncology (Williston Park). 2011 25 (2): 182-9

PMID: 21456390

Pancreatic cancer is the fourth leading cause of cancer death, and it is estimated that over 43,000 people would be diagnosed with and over 36,000 people would die of pancreatic cancer in the United States in 2010. Surgical resection remains the only chance for possible cure, but only 15% to 20% of patients newly diagnosed with pancreatic cancer are considered for surgical resection. Of these, the median five-year survival rate is still less than 20%, with most resections resulting in recurrent disease. This suggests that even seemingly resectable pancreatic cancer has microscopic systemic spread before operative intervention occurs. Both adjuvant and neoadjuvant therapies have been studied in an effort to improve survival for patients with resectable pancreatic cancer.

MeSH Terms (9)

Antineoplastic Combined Chemotherapy Protocols Chemotherapy, Adjuvant Clinical Trials as Topic Deoxycytidine Fluorouracil Humans Neoadjuvant Therapy Pancreatic Neoplasms Radiotherapy, Adjuvant

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