Executive Function in Adolescents With Type 1 Diabetes: Relationship to Adherence, Glycemic Control, and Psychosocial Outcomes.

Perez KM, Patel NJ, Lord JH, Savin KL, Monzon AD, Whittemore R, Jaser SS
J Pediatr Psychol. 2017 42 (6): 636-646

PMID: 28008003 · PMCID: PMC5896612 · DOI:10.1093/jpepsy/jsw093

Objective - Impairments in executive function (EF) skills have been observed in youth with type 1 diabetes (T1D), and these skills are critical for following the complex treatment regimen. This study examines parent reports of EF in relation to measures of adherence, glycemic control (A1c), and psychosocial outcomes (depression and quality of life) in adolescents with T1D. A total of 120 adolescents (aged 13-17 years, 52.5% female, 87.5% White) with T1D and their parents completed questionnaires. Glucometers were downloaded and A1c was obtained during clinical visits at the time of enrollment. The prevalence of clinically significant elevated scores on specific EF skills ranged from 11 to 18.6%. In multivariate analyses, parent-reported EF deficits were associated with poorer adherence and lower quality of life, explaining 13 and 12% of the variance, respectively. Adolescents with T1D exhibit specific EF deficits that may negatively impact their quality of life and their ability to engage in self-management activities.

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MeSH Terms (16)

Adolescent Biomarkers Blood Glucose Blood Glucose Self-Monitoring Cross-Sectional Studies Depression Diabetes Mellitus, Type 1 Executive Function Female Glycated Hemoglobin A Humans Male Patient Compliance Quality of Life Self-Management Surveys and Questionnaires

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