B Cell-Intrinsic mTORC1 Promotes Germinal Center-Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity.

Raybuck AL, Cho SH, Li J, Rogers MC, Lee K, Williams CL, Shlomchik M, Thomas JW, Chen J, Williams JV, Boothby MR
J Immunol. 2018 200 (8): 2627-2639

PMID: 29531165 · PMCID: PMC5893413 · DOI:10.4049/jimmunol.1701321

MeSH Terms (17)

Animals B-Lymphocytes Cell Differentiation Gene Expression Germinal Center Immunity, Humoral Immunoglobulin G Immunologic Memory Lymphocyte Activation Mechanistic Target of Rapamycin Complex 1 Mice Mice, Inbred C57BL Mutation Plasma Cells Proto-Oncogene Proteins c-bcl-6 Signal Transduction Transcription Factors

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