microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.

Marcais A, Blevins R, Graumann J, Feytout A, Dharmalingam G, Carroll T, Amado IF, Bruno L, Lee K, Walzer T, Mann M, Freitas AA, Boothby M, Fisher AG, Merkenschlager M
J Exp Med. 2014 211 (11): 2281-95

PMID: 25311506 · PMCID: PMC4203951 · DOI:10.1084/jem.20132059

MeSH Terms (18)

Animals Base Sequence Binding Sites CD4-Positive T-Lymphocytes Clonal Anergy Gene Expression Regulation Humans Interleukin-2 Lymphocyte Activation Mice Mice, Transgenic MicroRNAs Phosphorylation Proto-Oncogene Proteins c-akt Receptors, Antigen, T-Cell Ribonuclease III Signal Transduction TOR Serine-Threonine Kinases

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