STAT4 and T-bet are required for the plasticity of IFN-γ expression across Th2 ontogeny and influence changes in Ifng promoter DNA methylation.

Williams CL, Schilling MM, Cho SH, Lee K, Wei M, Aditi , Boothby M
J Immunol. 2013 191 (2): 678-87

PMID: 23761633 · PMCID: PMC3702659 · DOI:10.4049/jimmunol.1203360

MeSH Terms (18)

Animals Cell Differentiation Cells, Cultured CpG Islands DNA Methylation Immunologic Memory Interferon-gamma Interleukin-4 Lymphocyte Activation Mice Mice, Inbred BALB C Mice, Knockout Mice, Nude Promoter Regions, Genetic STAT4 Transcription Factor T-Box Domain Proteins Th1 Cells Th2 Cells

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