PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.

Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson PC, Barabási AL, Boothby M, Aikawa E, Singh SA, Aikawa M
Nat Commun. 2016 7: 12849

PMID: 27796300 · PMCID: PMC5095532 · DOI:10.1038/ncomms12849

MeSH Terms (25)

ADP-Ribosylation Animals Apoptosis Atherosclerosis Cell Survival Coronary Artery Disease Female Humans Inflammation Interferon-gamma Interleukin-4 Lipopolysaccharide Receptors Macrophage Activation Male Mice Mice, Inbred C57BL Neoplasm Proteins Phosphorylation Plaque, Atherosclerotic Poly(ADP-ribose) Polymerases RAW 264.7 Cells Ribose RNA Interference STAT1 Transcription Factor THP-1 Cells

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