Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.

Cho SH, Raybuck AL, Stengel K, Wei M, Beck TC, Volanakis E, Thomas JW, Hiebert S, Haase VH, Boothby MR
Nature. 2016 537 (7619): 234-238

PMID: 27501247 · PMCID: PMC5161594 · DOI:10.1038/nature19334

MeSH Terms (15)

Animals Antibodies B-Lymphocytes Cell Hypoxia Cell Proliferation Cell Survival Cytosine Deaminase Germinal Center Hypoxia Immunoglobulin Class Switching Mechanistic Target of Rapamycin Complex 1 Mice Mice, Inbred C57BL Multiprotein Complexes TOR Serine-Threonine Kinases

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