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Thomas Golper
Last active: 4/25/2016

Low-efficiency acute renal replacement therapy: role in acute kidney injury.

Marshall MR, Golper TA
Semin Dial. 2011 24 (2): 142-8

PMID: 21517979 · DOI:10.1111/j.1525-139X.2011.00829.x

The methodology, prescription, and delivery of acute renal replacement therapy are rapidly evolving areas. Recent clinical trials have provided clearer guidance around dosing targets for both therapy prescription and delivery. In this article, we discuss dialysis efficiency which is an area that subserves dialysis dose and pertains to manner in which a given dose is delivered. Dialysis efficiency directly effects the measurement and calculation of dose, and the occurrence of dialysis disequilibrium and hemodynamic instability. We provide recommendations around selecting the most appropriate clinical scenario and patients for higher-efficiency versus lower-efficiency therapy, and the implementation of therapy to achieve a given efficiency.

© 2011 Wiley Periodicals, Inc.

MeSH Terms (10)

Acute Kidney Injury Brain Edema Comorbidity Humans Intensive Care Units Renal Replacement Therapy Risk Factors Shock, Cardiogenic Syndrome Terminology as Topic

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