Borden Lacy
Last active: 3/24/2020

Small Molecule Inhibitor Screen Reveals Calcium Channel Signaling as a Mechanistic Mediator of TcdB-Induced Necrosis.

Farrow MA, Chumber NM, Bloch SC, King M, Moton-Melancon K, Shupe J, Washington MK, Spiller BW, Lacy DB
ACS Chem Biol. 2020 15 (5): 1212-1221

PMID: 31909964 · PMCID: PMC7230009 · DOI:10.1021/acschembio.9b00906

MeSH Terms (20)

Actin Cytoskeleton Animals Anti-Infective Agents Bacterial Toxins Calcium Channel Blockers Calcium Channels Calcium Signaling Clostridioides difficile Cytokines Dihydropyridines Dose-Response Relationship, Drug Drug Evaluation, Preclinical Glucosyltransferases Humans Kinetics Mice NADPH Oxidases Necrosis Reactive Oxygen Species Virulence Factors

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