Borden Lacy
Last active: 3/24/2020

A neutralizing antibody that blocks delivery of the enzymatic cargo of toxin TcdB into host cells.

Kroh HK, Chandrasekaran R, Zhang Z, Rosenthal K, Woods R, Jin X, Nyborg AC, Rainey GJ, Warrener P, Melnyk RA, Spiller BW, Lacy DB
J Biol Chem. 2018 293 (3): 941-952

PMID: 29180448 · PMCID: PMC5777265 · DOI:10.1074/jbc.M117.813428

MeSH Terms (13)

Antibodies, Monoclonal Antibodies, Neutralizing Bacterial Toxins Caco-2 Cells Clostridioides difficile Crystallography, X-Ray Cytosol Enterotoxins Humans Hydrogen-Ion Concentration Microscopy, Electron rac1 GTP-Binding Protein Rubidium

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