Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts.

Guo L, Chen Z, Amarnath V, Yancey PG, Van Lenten BJ, Savage JR, Fazio S, Linton MF, Davies SS
Antioxid Redox Signal. 2015 22 (18): 1633-45

PMID: 25751734 · PMCID: PMC4485367 · DOI:10.1089/ars.2014.6078

MeSH Terms (14)

Aldehydes Animals Humans Inflammation Lipids Macrophages Male Mice, Inbred C57BL Mice, Knockout NF-kappa B Phosphatidylethanolamines Prostaglandins E Pyrrolidines Receptor for Advanced Glycation End Products

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