James Crowe
Faculty Member
Last active: 3/31/2020

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies.

Bornholdt ZA, Ndungo E, Fusco ML, Bale S, Flyak AI, Crowe JE, Chandran K, Saphire EO
mBio. 2016 7 (1): e02154-15

PMID: 26908579 · PMCID: PMC4791852 · DOI:10.1128/mBio.02154-15

MeSH Terms (17)

Antibodies, Neutralizing Antibodies, Viral Carrier Proteins Cell Line Crystallography, X-Ray Ebolavirus Hemorrhagic Fever, Ebola Humans Hydrophobic and Hydrophilic Interactions Intracellular Signaling Peptides and Proteins Membrane Glycoproteins Mutagenesis Mutation Protein Binding Receptors, Virus Viral Envelope Proteins Virus Internalization

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