Daniel Liebler
Faculty Member
Last active: 2/15/2016

Safety assessment of stearyl heptanoate and related stearyl alkanoates as used in cosmetics.

Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler D, Marks JG, Shank RC, Slaga TJ, Snyder PW, Andersen FA
Int J Toxicol. 2012 31 (5 Suppl): 141S-6S

PMID: 23064772 · DOI:10.1177/1091581812460408

Stearyl heptanoate is an ester of stearyl alcohol and heptanoic acid that functions in cosmetics as a skin conditioning agent and is in the general class of chemicals called stearyl alkanoates. Stearyl caprylate, stearyl palmitate, stearyl stearate, stearyl behenate, and stearyl olivate are stearyl alkanoates with similar chemical structures, toxicokinetics, and functions in cosmetics. These water-insoluble stearyl alkanoates, when metabolized, yield stearyl alcohol and a corresponding fatty acid. The available information supports the safety of all of the related stearyl alkanoates. The Expert Panel concluded that stearyl heptanoate, stearyl caprylate, stearyl palmitate, stearyl stearate, stearyl behenate, and stearyl olivate are safe in the present practices of use and concentration.

MeSH Terms (11)

Administration, Cutaneous Animals Consumer Product Safety Cosmetics Dermatologic Agents Heptanoates Humans Skin Care Stearates Toxicity Tests Waxes

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