Daniel Liebler
Faculty Member
Last active: 2/15/2016

Safety assessment of decyl glucoside and other alkyl glucosides as used in cosmetics.

Fiume MM, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler D, Marks JG, Shank RC, Slaga TJ, Snyder PW, Andersen FA
Int J Toxicol. 2013 32 (5 Suppl): 22S-48S

PMID: 24174472 · DOI:10.1177/1091581813497764

The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of 19 alkyl glucosides as used in cosmetics and concluded that these ingredients are safe in the present practices of use and concentration when formulated to be nonirritating. Most of these ingredients function as surfactants in cosmetics, but some have additional functions as skin-conditioning agents, hair-conditioning agents, or emulsion stabilizers. The Panel reviewed the available animal and clinical data on these ingredients. Since glucoside hydrolases in human skin are likely to break down these ingredients to release their respective fatty acids and glucose, the Panel also reviewed CIR reports on the safety of fatty alcohols and were able to extrapolate data from those previous reports to support safety.

MeSH Terms (8)

Animals Consumer Product Safety Cosmetics Glucosides Humans Mutagenicity Tests Reproduction Skin

Connections (1)

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