Dan Roden
Faculty Member
Last active: 3/24/2020

An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1.

Yang T, Smith JA, Leake BF, Sanders CR, Meiler J, Roden DM
Mol Pharmacol. 2013 83 (2): 481-9

PMID: 23193163 · PMCID: PMC3558809 · DOI:10.1124/mol.112.081513

MeSH Terms (15)

Alanine Allosteric Regulation Animals Binding Sites Cell Line CHO Cells Cricetinae Cysteine Heart Humans KCNQ1 Potassium Channel Models, Molecular Mutagenesis, Site-Directed Myocardium Quinidine

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