Dan Roden
Faculty Member
Last active: 3/24/2020

A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes.

Kääb S, Crawford DC, Sinner MF, Behr ER, Kannankeril PJ, Wilde AA, Bezzina CR, Schulze-Bahr E, Guicheney P, Bishopric NH, Myerburg RJ, Schott JJ, Pfeufer A, Beckmann BM, Martens E, Zhang T, Stallmeyer B, Zumhagen S, Denjoy I, Bardai A, Van Gelder IC, Jamshidi Y, Dalageorgou C, Marshall V, Jeffery S, Shakir S, Camm AJ, Steinbeck G, Perz S, Lichtner P, Meitinger T, Peters A, Wichmann HE, Ingram C, Bradford Y, Carter S, Norris K, Ritchie MD, George AL, Roden DM
Circ Cardiovasc Genet. 2012 5 (1): 91-9

PMID: 22100668 · PMCID: PMC3288202 · DOI:10.1161/CIRCGENETICS.111.960930

MeSH Terms (19)

Aged Aged, 80 and over Alleles Amino Acid Substitution Anti-Arrhythmia Agents Case-Control Studies Cohort Studies Female Genotype Haplotypes Humans Long QT Syndrome Male Middle Aged Odds Ratio Polymorphism, Single Nucleotide Potassium Potassium Channels, Voltage-Gated Torsades de Pointes

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