Dan Roden
Faculty Member
Last active: 3/24/2020

Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro.

Watanabe H, Yang T, Stroud DM, Lowe JS, Harris L, Atack TC, Wang DW, Hipkens SB, Leake B, Hall L, Kupershmidt S, Chopra N, Magnuson MA, Tanabe N, Knollmann BC, George AL, Roden DM
Circulation. 2011 124 (9): 1001-11

PMID: 21824921 · PMCID: PMC3297976 · DOI:10.1161/CIRCULATIONAHA.110.987248

MeSH Terms (19)

Animals Atrial Flutter Cardiomyopathy, Dilated CHO Cells Cricetinae Cricetulus Defibrillators, Implantable Electrocardiography Humans Male Mice Mice, Transgenic Mutation, Missense Myocardial Contraction NAV1.5 Voltage-Gated Sodium Channel Sick Sinus Syndrome Sodium Channels Treatment Outcome Young Adult

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